Influences of compounds on metallothionein concentration in mouse tissues. II. Decrease of pancreatic metallothionein concentration by n-hexane.

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Down-Regulation of Metallothionein 1 and 2 after Exposure to Electromagnetic Field in Mouse Testis

Background: It is proved that testis is sensitive to electromagnetic field (EMF) and its damage results in infertility. Exposure to EMF induces reactive oxygen species production and affects on anti-oxidants defense mechanisms. Metallothionein (MT) is a name for a group of low molecular weight (6-7 kDa), sulfhydryl rich proteins. Expression of MT1 and MT2 genes in testis tissue after EMF exposu...

متن کامل

comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...

15 صفحه اول

Glucose Regulates Free Cytosolic Zn2+ Concentration, Slc39 (ZiP), and Metallothionein Gene Expression in Primary Pancreatic Islet β-Cells*

Zn²⁺ is an important cofactor for insulin biosynthesis and storage in pancreatic β-cells. Correspondingly, polymorphisms in the SLC30A8 gene, encoding the secretory granule Zn²⁺ transporter ZnT8, are associated with type 2 diabetes risk. Using a genetically engineered (FRET)-based sensor (eCALWY-4), we show here that elevated glucose time-dependently increases free cytosolic Zn²⁺ ([Zn²⁺](cyt)) ...

متن کامل

Concentration Dependence of Transport and Corrected Diffusivities of n-Hexane in Silicalite Measured by QENS

1. Introduction Separation induced by kinetic effects using zeolite as a shape selective adsorbent is of great industrial concern. The control of diffusion process, requiring a precise knowledge of self-, transport and corrected diffusivities (D self , D t and D C , respectively), is essential for the design of industrial applications. D self and D t are usually measured directly by microscopic...

متن کامل

High Concentration of Cytoplasmic Metallothionein Increased Resistance to Chlorambucil in Cultured Cells with a Updated Version

Cultured cells with elevated levels of cytoplasmic metalloidionein (MT), a small-molecular-weight protein extremely rich in cysteine. showed resistance against the alkylating drug chlorambucil. One human epithelial line (HE) and one mouse fibroblast line (CI 1D) were used, as well as substrains of both cell lines (HE10oand CI 1D10o).The substrains contain large amounts of MT. Dose-survival curv...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Eisei kagaku

سال: 1988

ISSN: 0013-273X

DOI: 10.1248/jhs1956.34.446